Eve, the genetically engineered bio-weapon that looks like a young girl from the Anime and Manga Black Cat comes in at number number two on the list.
Using nanotechnology Eve can transform her body into various types of offensive and defensive weapons.
At first she could only do parts, but later, she developed the ability to transform her entire body into a weapon, though it puts quite a strain on her.
http://anime-times.blogspot.com/2010/04/top-ten-anime-girls-eve-black-cat.html